KondratYuk R.V., Trivailo M.S., Saverchenko V.G., shapharenko N.V.

National Technical University of Ukraine «KPI»

THE SPHERICAL MOTION OF TRAPEZOID PLATE

The utility model concerns to the biotechnology and can be used for the cultivation of cells by manufacturing of viral vaccines and various biologically active preparations.

The known device for the cultivation of cells (DC) which contains the cylindrical case with technological branch pipes and a mixing disk from non-magnetic material cantileverly fixed at the bottom of the case, and also a drive in the form of magnets periodically co-operating among themselves and established on a disk and on a rotor (for example, А.с. The USSR № 1306944, С12 M3/00, 1987).

The lack of this DC consists in low efficiency of mixing which is caused by console fastening to a disk and reduces productivity of technological process.

The closest to the utility model for a technical essence and achievable effect accepted as a prototype is DC that contains the cylindrical case with the bottom from non-magnetic material and technological branch pipes and the disk executed from a magnetic material with the central core on one party, and a mixing element on other part which it is executed in the form of the central core placed at the bottom of the case, and also the drive of a disk in the form of in regular intervals located on a circle under the bottom of the case of electromagnets which are consistently connected to the power supply (for example, the patent of Ukraine for useful model № 12120, С12M3/00, 2006).

The lack of known DC consists also in low efficiency of mixing which slows down growth of cells and leads to decline of productivity of manufacturing of vaccines.

The specified lack is caused by that the mixing element in the form of a core at the movement does not provide movement of the central parts of a working liquid in radial directions and on height, and carries out only circular moving of insignificant volume.

The basis of the utility model is the task of improvement of DC in which the activization of movement of a working liquid in its central and peripheral parts by updating of the mixing element which raises intensity and uniformity of mixing is provided, leads to growth of productivity of process.

The task is solving be that in DC which contains the cylindrical case with the bottom from non-magnetic material and technological branch pipes and the executed disk placed at the bottom of the case from magnetic material with the central basic core on one part and the mixing element on other part, and also a drive of a disk in the form of electromagnets located on a circle under a bottom of the case in regular intervals which are consistently connected to the power supply, according to the utility model the new there is that the mixing element is executed in other geometrical form in the form of a plate.

In the most acceptable example of performance of DC the plate has the form of a trapeze which is attached by a bigger basis to a disk.

Manufacturing of a mixing element in the form of a plate provides active mass exchange of a working liquid in radial directions and on height as the surface of its (the element) of interaction with a working liquid owing to what efficiency of mixing considerably raises essentially increases absent in the nearest analogue.

The realization of a plate in the form of a trapeze increases the area of interaction of a working liquid with the mixing element which in addition raises the intensity of the mass exchange.

On Fig. 1 the offered DC is represented in the section: on Fig. 1, b, – section А-А on Fig. 1, a.

DC contains the cylindrical case 1 with a bottom 2 of non-magnetic material and a cover 3 and technological branch pipes 4 for introduction and removal of the working (cultural) liquids.

At the bottom of the case 1 a mixing disk 5 «d» in the diameter executed from a magnetic material with the central basic core 6 located. On the another (top) part of the disk 5, fixed, for example, welded additional the mixing element executed in the form of a disk of a plate 7 located in diametrical plane, with the sizes «В×H» (Fig. 1, b), which blocks the level of the working liquid 8 in the case 1. The plate 7, except the rectangular, may have the form of the trapeze 9 (on Fig.1, b shown by the dotted line), which is connected to a disk 5 by the bigger base which enlarge its surface for the interaction with the working liquid 8.

The drive of a disk 5 is carried out by the electromagnets 10 located under the bottom 2 in regular intervals on a circle of which in a pulse program mode are serially connected to the power supply 11.

DC works in the following way.

After the turning on of the drive, electromagnets 10 create a rotating magnetic field which draws a disk 5 owing to what it comes to a oscillatory sinusoidal movement around the core 6. Shaking disk 5 and a plate 7 is carried out the mixing of a working liquid 8, a disk 5 – mainly benthonic layer, and a plate 7 – the top and average layers. Thus, the plate 7, by its moving, for example, behind an arrow 12, moves one wall the central part 13 of a working liquid (with the area «В×H») in radial direction and force out the parietal part 14 through the gaps «δ» (Fig. 1, b) to the back side. The active mixing (interfusion) take place due to the simultaneous moving of the central and periphery parts of the working liquid

Besides, at the fluctuation of a plate 7 in a direction of an arrow 15 (Fig. 1, a) owing to different diameters of the a disk 5 «d» and diameter «d₁» of the bottoms of the case 1 which contact among themselves in a place "a" a friction gear appears, the plate 7 comes to slow rotating movement for an arrow 16 (Fig. 1, b), that intensifies mixing of a working liquid in a circular direction.

In comparison with the nearest analogue, the offered DC by the increase of the surface of the mixing element 7, provides additional mass exchange of a working liquid and raises uniformity of distribution in it of nutrients and cells which improves conditions for them growth and leads to increase of productivity of technological process.

The offered useful model is simple enough for technical realisation and, at the same time, improves quality of clearing of foam on a surface of a working liquid.